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Functional characterization of FBXL7 as a novel player in human cancers

F-box and leucine-rich repeat protein 7 (FBXL7), an F-box protein responsible for substrate recognition by the SKP1-Cullin-1-F-box (SCF) ubiquitin ligases, plays an emerging role in the regulation of tumorigenesis and tumor progression. FBXL7 promotes polyubiquitylation and degradation of diverse su...

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Detalles Bibliográficos
Autores principales: Wang, Yue, Shen, Xiao, Gong, Longyuan, Zhao, Yongchao, Xiong, Xiufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338262/
https://www.ncbi.nlm.nih.gov/pubmed/35906197
http://dx.doi.org/10.1038/s41420-022-01143-w