A multimodal iPSC platform for cystic fibrosis drug testing

Cystic fibrosis is a monogenic lung disease caused by dysfunction of the cystic fibrosis transmembrane conductance regulator anion channel, resulting in significant morbidity and mortality. The progress in elucidating the role of CFTR using established animal and cell-based models led to the recent...

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Detalles Bibliográficos
Autores principales: Berical, Andrew, Lee, Rhianna E., Lu, Junjie, Beermann, Mary Lou, Le Suer, Jake A., Mithal, Aditya, Thomas, Dylan, Ranallo, Nicole, Peasley, Megan, Stuffer, Alex, Bukis, Katherine, Seymour, Rebecca, Harrington, Jan, Coote, Kevin, Valley, Hillary, Hurley, Killian, McNally, Paul, Mostoslavsky, Gustavo, Mahoney, John, Randell, Scott H., Hawkins, Finn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338271/
https://www.ncbi.nlm.nih.gov/pubmed/35906215
http://dx.doi.org/10.1038/s41467-022-31854-8

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