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FLASHIda enables intelligent data acquisition for top–down proteomics to boost proteoform identification counts
The detailed analysis and structural characterization of proteoforms by top-down proteomics (TDP) has gained a lot of interest in biomedical research. Data-dependent acquisition (DDA) of intact proteins is non-trivial due to the diversity and complexity of proteoforms. Dedicated acquisition methods...
Autores principales: | Jeong, Kyowon, Babović, Maša, Gorshkov, Vladimir, Kim, Jihyung, Jensen, Ole N., Kohlbacher, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338294/ https://www.ncbi.nlm.nih.gov/pubmed/35906205 http://dx.doi.org/10.1038/s41467-022-31922-z |
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