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CD95 gene deletion may reduce clonogenic growth and invasiveness of human glioblastoma cells in a CD95 ligand-independent manner

CD95 (Fas/APO-1) is a multifunctional cell surface receptor with antithetic roles. First described to mediate cell death, interactions of CD95 with its natural ligand, CD95L, have also been described to induce tumor-promoting signaling leading to proliferation, invasion and stem cell maintenance, ma...

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Detalles Bibliográficos
Autores principales: Quijano-Rubio, Clara, Silginer, Manuela, Weller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338300/
https://www.ncbi.nlm.nih.gov/pubmed/35906203
http://dx.doi.org/10.1038/s41420-022-01133-y