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Intratunical injection of rat-derived bone marrow mesenchymal stem cells prevents fibrosis and is associated with increased Smad7 expression in a rat model of Peyronie’s disease

OBJECTIVE: Peyronie’s disease (PD) is a fibrotic disorder of the penis, but effective treatments are lacking. Here, we observed the effects of rat-derived bone marrow mesenchymal stem cells (BMSCs) injection in the active phase and chronic phase in a rat model of PD, and the possible mechanism was a...

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Detalles Bibliográficos
Autores principales: Wang, Wenting, Ding, Weifang, Zhang, Xuebao, Wu, Shuang, Yu, Tianxi, Cui, Xin, Xie, Yaqi, Yang, Diandong, Lin, Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338499/
https://www.ncbi.nlm.nih.gov/pubmed/35908015
http://dx.doi.org/10.1186/s13287-022-03090-w