Cargando…

Marked aggravation of pyrethroid resistance in major malaria vectors in Malawi between 2014 and 2021 is partly linked with increased expression of P450 alleles

BACKGROUND: Increased intensity of pyrethroid resistance is threatening the effectiveness of insecticide-based interventions to control malaria in Africa. Assessing the extent of this aggravation and its impact on the efficacy of these tools is vital to ensure the continued control of major vectors....

Descripción completa

Detalles Bibliográficos
Autores principales:	Menze, Benjamin D., Tchouakui, Magellan, Mugenzi, Leon M. J., Tchapga, Williams, Tchoupo, Micareme, Wondji, Murielle J., Chiumia, Martin, Mzilahowa, Themba, Wondji, Charles S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338535/ https://www.ncbi.nlm.nih.gov/pubmed/35907831 http://dx.doi.org/10.1186/s12879-022-07596-9

Ejemplares similares

Pyrethroid Resistance Aggravation in Ugandan Malaria Vectors Is Reducing Bednet Efficacy
por: Tchouakui, Magellan, et al.
Publicado: (2021)

Experimental Hut Trials Reveal That CYP6P9a/b P450 Alleles Are Reducing the Efficacy of Pyrethroid-Only Olyset Net against the Malaria Vector Anopheles funestus but PBO-Based Olyset Plus Net Remains Effective
por: Menze, Benjamin D., et al.
Publicado: (2022)

Combined over-expression of two cytochrome P450 genes exacerbates the fitness cost of pyrethroid resistance in the major African malaria vector Anopheles funestus
por: Tchouakui, Magellan, et al.
Publicado: (2021)

Correction: Cytochrome P450 metabolic resistance (CYP6P9a) to pyrethroids imposes a fitness cost in the major African malaria vector Anopheles funestus
por: Tchouakui, Magellan, et al.
Publicado: (2020)

A 6.5kb Intergenic Structural Variation Exacerbates the Fitness Cost of P450-Based Metabolic Resistance in the Major African Malaria Vector Anopheles funestus
por: Tchouakui, Magellan, et al.
Publicado: (2022)

Cis-regulatory CYP6P9b P450 variants associated with loss of insecticide-treated bed net efficacy against Anopheles funestus
por: Mugenzi, Leon M. J., et al.
Publicado: (2019)

Escalation of Pyrethroid Resistance in the Malaria Vector Anopheles funestus Induces a Loss of Efficacy of Piperonyl Butoxide–Based Insecticide-Treated Nets in Mozambique
por: Riveron, Jacob M, et al.
Publicado: (2019)

Escalating pyrethroid resistance in two major malaria vectors Anopheles funestus and Anopheles gambiae (s.l.) in Atatam, Southern Ghana
por: Mugenzi, Leon M. J., et al.
Publicado: (2022)

A combination of metabolic resistance and high frequency of the 1014F kdr mutation is driving pyrethroid resistance in Anopheles coluzzii population from Guinea savanna of Cameroon
por: Fadel, Amen N., et al.
Publicado: (2019)

Bionomics and insecticides resistance profiling of malaria vectors at a selected site for experimental hut trials in central Cameroon
por: Menze, Benjamin D., et al.
Publicado: (2018)

Fitness cost of target-site and metabolic resistance to pyrethroids drives restoration of susceptibility in a highly resistant Anopheles gambiae population from Uganda
por: Tchouakui, Magellan, et al.
Publicado: (2022)

An Experimental Hut Evaluation of PBO-Based and Pyrethroid-Only Nets against the Malaria Vector Anopheles funestus Reveals a Loss of Bed Nets Efficacy Associated with GSTe2 Metabolic Resistance
por: Menze, Benjamin D., et al.
Publicado: (2020)

Xeno-monitoring of molecular drivers of artemisinin and partner drug resistance in P. falciparum populations in malaria vectors across Cameroon
por: Nkemngo, Francis N., et al.
Publicado: (2022)

Reduced performance of community bednets against pyrethroid-resistant Anopheles funestus and Anopheles gambiae, major malaria vectors in Cameroon
por: Ngongang-Yipmo, Emilie S., et al.
Publicado: (2022)

Evidence of intensification of pyrethroid resistance in the major malaria vectors in Kinshasa, Democratic Republic of Congo
por: Nguiffo-Nguete, Daniel, et al.
Publicado: (2023)

Anopheles funestus Populations across Africa Are Broadly Susceptible to Neonicotinoids but with Signals of Possible Cross-Resistance from the GSTe2 Gene
por: Assatse, Tatiane, et al.
Publicado: (2023)

High insecticide resistance in the major malaria vector Anopheles coluzzii in Chad Republic
por: Ibrahim, Sulaiman S., et al.
Publicado: (2019)

Investigation of the influence of a glutathione S-transferase metabolic resistance to pyrethroids/DDT on mating competitiveness in males of the African malaria vector, Anopheles funestus
por: Tchouakui, Magellan, et al.
Publicado: (2019)

A marker of glutathione S-transferase-mediated resistance to insecticides is associated with higher Plasmodium infection in the African malaria vector Anopheles funestus
por: Tchouakui, Magellan, et al.
Publicado: (2019)

CYP6P9-Driven Signatures of Selective Sweep of Metabolic Resistance to Pyrethroids in the Malaria Vector Anopheles funestus Reveal Contemporary Barriers to Gene Flow
por: Djuicy, Delia Doreen, et al.
Publicado: (2020)

Rise of multiple insecticide resistance in Anopheles funestus in Malawi: a major concern for malaria vector control
por: Riveron, Jacob M., et al.
Publicado: (2015)

Influence of GST- and P450-based metabolic resistance to pyrethroids on blood feeding in the major African malaria vector Anopheles funestus
por: Nouage, Lynda, et al.
Publicado: (2020)

Detection of a reduced susceptibility to chlorfenapyr in the malaria vector Anopheles gambiae contrasts with full susceptibility in Anopheles funestus across Africa
por: Tchouakui, Magellan, et al.
Publicado: (2023)

Contrasting Patterns of Asaia Association with Pyrethroid Resistance Escalation between the Malaria Vectors Anopheles funestus and Anopheles gambiae
por: Djondji Kamga, Fleuriane Metissa, et al.
Publicado: (2023)

The duplicated P450s CYP6P9a/b drive carbamates and pyrethroids cross-resistance in the major African malaria vector Anopheles funestus
por: Mugenzi, Leon M. J., et al.
Publicado: (2023)

Comparative study of the effect of solvents on the efficacy of neonicotinoid insecticides against malaria vector populations across Africa
por: Tchouakui, Magellan, et al.
Publicado: (2022)

Genetic Diversity of Cytochrome P450s CYP6M2 and CYP6P4 Associated with Pyrethroid Resistance in the Major Malaria Vectors Anopheles coluzzii and Anopheles gambiae from Yaoundé, Cameroon
por: Fotso-Toguem, Yvan, et al.
Publicado: (2022)

High efficacy of chlorfenapyr-based net Interceptor(®) G2 against pyrethroid-resistant malaria vectors from Cameroon
por: Tchouakui, Magellan, et al.
Publicado: (2023)

Pyrethroid Resistance in the Major Malaria Vector Anopheles funestus is Exacerbated by Overexpression and Overactivity of the P450 CYP6AA1 Across Africa
por: Ibrahim, Sulaiman S., et al.
Publicado: (2018)

RNAseq-based gene expression profiling of the Anopheles funestus pyrethroid-resistant strain FUMOZ highlights the predominant role of the duplicated CYP6P9a/b cytochrome P450s
por: Wondji, Charles S, et al.
Publicado: (2021)

Entomological longitudinal surveys in two contrasted eco-climatic settings in Cameroon reveal a high malaria transmission from Anopheles funestus associated with GSTe2 metabolic resistance
por: Natchema S. Fonkou, Brice, et al.
Publicado: (2023)

Fitness Costs of the Glutathione S-Transferase Epsilon 2 (L119F-GSTe2) Mediated Metabolic Resistance to Insecticides in the Major African Malaria Vector Anopheles Funestus
por: Tchouakui, Magellan, et al.
Publicado: (2018)

The highly polymorphic CYP6M7 cytochrome P450 gene partners with the directionally selected CYP6P9a and CYP6P9b genes to expand the pyrethroid resistance front in the malaria vector Anopheles funestus in Africa
por: Riveron, Jacob M, et al.
Publicado: (2014)

Genome-Wide Transcriptional Analysis and Functional Validation Linked a Cluster of Epsilon Glutathione S-Transferases with Insecticide Resistance in the Major Malaria Vector Anopheles funestus across Africa
por: Kouamo, Mersimine F. M., et al.
Publicado: (2021)

Temporal distribution and insecticide resistance profile of two major arbovirus vectors Aedes aegypti and Aedes albopictus in Yaoundé, the capital city of Cameroon
por: Kamgang, Basile, et al.
Publicado: (2017)

Exposure to the insecticide-treated bednet PermaNet 2.0 reduces the longevity of the wild African malaria vector Anopheles funestus but GSTe2-resistant mosquitoes live longer
por: Tchakounte, Ange, et al.
Publicado: (2019)

Molecular Drivers of Multiple and Elevated Resistance to Insecticides in a Population of the Malaria Vector Anopheles gambiae in Agriculture Hotspot of West Cameroon
por: Tepa, Arnaud, et al.
Publicado: (2022)

Overexpression of Two Members of D7 Salivary Genes Family is Associated with Pyrethroid Resistance in the Malaria Vector Anopheles Funestus s.s. but Not in Anopheles Gambiae in Cameroon
por: Elanga-Ndille, Emmanuel, et al.
Publicado: (2019)

Exploring insecticide resistance mechanisms in three major malaria vectors from Bangui in Central African Republic
por: Kamgang, Basile, et al.
Publicado: (2018)

The cytochrome P450 CYP6P4 is responsible for the high pyrethroid resistance in knockdown resistance-free Anopheles arabiensis
por: Ibrahim, Sulaiman S., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_4o4m9j7p46act510l1ttcrhdq0