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The RNA-binding protein PCBP1 represses lung adenocarcinoma progression by stabilizing DKK1 mRNA and subsequently downregulating β-catenin

BACKGROUND: PolyC-RNA-binding protein 1 (PCBP1) functions as a tumour suppressor and RNA regulator that is downregulated in human cancers. Here, we aimed to reveal the biological function of PCBP1 in lung adenocarcinoma (LUAD). METHODS: First, PCBP1 was identified as an important biomarker that main...

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Detalles Bibliográficos
Autores principales:	Zheng, Yujia, Zhou, Zheng, Wei, Ran, Xiao, Chu, Zhang, Hao, Fan, Tao, Zheng, Bo, Li, Chunxiang, He, Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338556/ https://www.ncbi.nlm.nih.gov/pubmed/35907982 http://dx.doi.org/10.1186/s12967-022-03552-y

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