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Strategies to improve homology-based repair outcomes following CRISPR-based gene editing in mosquitoes: lessons in how to keep any repair disruptions local

Programmable gene editing systems such as CRISPR-Cas have made mosquito genome engineering more practical and accessible, catalyzing the development of cutting-edge genetic methods of disease vector control. This progress, however, has been limited by the low efficiency of homology-directed repair (...

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Detalles Bibliográficos
Autores principales: Finney, Micaela, Romanowski, Joseph, Adelman, Zach N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338592/
https://www.ncbi.nlm.nih.gov/pubmed/35908059
http://dx.doi.org/10.1186/s12985-022-01859-2

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