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Ultra-thin layered double hydroxide-mediated photothermal therapy combine with asynchronous blockade of PD-L1 and NR2F6 inhibit hepatocellular carcinoma
BACKGROUND: The efficacy of immune checkpoint blockade (ICB), in the treatment of hepatocellular carcinoma (HCC), is limited due to low levels of tumor-infiltrating T lymphocytes and deficient checkpoint blockade in this immunologically "cool" tumor. Thus, combination approaches are needed...
Autores principales: | Lu, Yuan-Fei, Zhou, Jia-Ping, Zhou, Qiao-Mei, Yang, Xiao-Yan, Wang, Xiao-Jie, Yu, Jie-Ni, Zhang, Jin-Guo, Du, Yong-Zhong, Yu, Ri-Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338598/ https://www.ncbi.nlm.nih.gov/pubmed/35907841 http://dx.doi.org/10.1186/s12951-022-01565-9 |
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