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Concomitant primary angiosarcoma and invasive carcinoma of the breast: a case report

Collision tumor is a rare entity composed of two different tumors that occur in close to one another and maintain distinct borders. Only few cases have been reported in the breast. We report the first case of concomitant and adjacent primary angiosarcoma (PBAS) and invasive carcinoma of the breast (...

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Autores principales: Zghal, Mouna, Triki, Meriam, Khanfir, Fatma, Bouhamed, Marwa, Mallouli, Imen, Louati, Doulira, Boudawara, Tahya, Saguem, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338697/
https://www.ncbi.nlm.nih.gov/pubmed/35949476
http://dx.doi.org/10.11604/pamj.2022.42.70.31484
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author Zghal, Mouna
Triki, Meriam
Khanfir, Fatma
Bouhamed, Marwa
Mallouli, Imen
Louati, Doulira
Boudawara, Tahya
Saguem, Ines
author_facet Zghal, Mouna
Triki, Meriam
Khanfir, Fatma
Bouhamed, Marwa
Mallouli, Imen
Louati, Doulira
Boudawara, Tahya
Saguem, Ines
author_sort Zghal, Mouna
collection PubMed
description Collision tumor is a rare entity composed of two different tumors that occur in close to one another and maintain distinct borders. Only few cases have been reported in the breast. We report the first case of concomitant and adjacent primary angiosarcoma (PBAS) and invasive carcinoma of the breast (IBC), in a 45-year-old patient which presented with a lump in her right breast. Biopsy revealed PBAS. She underwent mastectomy. Gross examination showed a hemorrhagic and spongy tumor in contact with a second small grayish-white mass. Histologically, the hemorrhagic tumor was consistent with a high grade (HG) PBAS; the second mass was consistent with an IBC with no images of histological admixture. The diagnosis of a collision tumor composed of HG PBAS and IBC was established. During follow-up, the patient developed ovarian angiosarcomatous metastasis. The diagnosis of breast collision tumor is very uncommon and hence is challenging for pathologist. Careful gross and microscopic examinations help in establishing the appropriate diagnosis.
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spelling pubmed-93386972022-08-09 Concomitant primary angiosarcoma and invasive carcinoma of the breast: a case report Zghal, Mouna Triki, Meriam Khanfir, Fatma Bouhamed, Marwa Mallouli, Imen Louati, Doulira Boudawara, Tahya Saguem, Ines Pan Afr Med J Case Report Collision tumor is a rare entity composed of two different tumors that occur in close to one another and maintain distinct borders. Only few cases have been reported in the breast. We report the first case of concomitant and adjacent primary angiosarcoma (PBAS) and invasive carcinoma of the breast (IBC), in a 45-year-old patient which presented with a lump in her right breast. Biopsy revealed PBAS. She underwent mastectomy. Gross examination showed a hemorrhagic and spongy tumor in contact with a second small grayish-white mass. Histologically, the hemorrhagic tumor was consistent with a high grade (HG) PBAS; the second mass was consistent with an IBC with no images of histological admixture. The diagnosis of a collision tumor composed of HG PBAS and IBC was established. During follow-up, the patient developed ovarian angiosarcomatous metastasis. The diagnosis of breast collision tumor is very uncommon and hence is challenging for pathologist. Careful gross and microscopic examinations help in establishing the appropriate diagnosis. The African Field Epidemiology Network 2022-05-25 /pmc/articles/PMC9338697/ /pubmed/35949476 http://dx.doi.org/10.11604/pamj.2022.42.70.31484 Text en Copyright: Mouna Zghal et al. https://creativecommons.org/licenses/by/4.0/The Pan African Medical Journal (ISSN: 1937-8688). This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Zghal, Mouna
Triki, Meriam
Khanfir, Fatma
Bouhamed, Marwa
Mallouli, Imen
Louati, Doulira
Boudawara, Tahya
Saguem, Ines
Concomitant primary angiosarcoma and invasive carcinoma of the breast: a case report
title Concomitant primary angiosarcoma and invasive carcinoma of the breast: a case report
title_full Concomitant primary angiosarcoma and invasive carcinoma of the breast: a case report
title_fullStr Concomitant primary angiosarcoma and invasive carcinoma of the breast: a case report
title_full_unstemmed Concomitant primary angiosarcoma and invasive carcinoma of the breast: a case report
title_short Concomitant primary angiosarcoma and invasive carcinoma of the breast: a case report
title_sort concomitant primary angiosarcoma and invasive carcinoma of the breast: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338697/
https://www.ncbi.nlm.nih.gov/pubmed/35949476
http://dx.doi.org/10.11604/pamj.2022.42.70.31484
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