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Evolution of ACE2-independent SARS-CoV-2 infection and mouse adaption after passage in cells expressing human and mouse ACE2

Human ACE2 Human angiotensin converting enzyme 2 (hACE2) is the key cell attachment and entry receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), with the original SARS-CoV-2 isolates unable to use mouse ACE2 (mACE2). Herein we describe the emergence of a SARS-CoV-2 strain cap...

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Detalles Bibliográficos
Autores principales:	Yan, Kexin, Dumenil, Troy, Tang, Bing, Le, Thuy T, Bishop, Cameron R, Suhrbier, Andreas, Rawle, Daniel J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338707/ https://www.ncbi.nlm.nih.gov/pubmed/35919871 http://dx.doi.org/10.1093/ve/veac063

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