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Irisin Ameliorates Intervertebral Disc Degeneration by Activating LATS/YAP/CTGF Signaling

Unbalanced metabolism of an extracellular matrix (ECM) in nucleus pulposus cells (NPCs) is widely acknowledged as the primary cause of intervertebral disc degeneration (IDD). Irisin, a novel myokine, is cleaved from fibronectin type III domain-containing 5 (FNDC5) and has recently been proven to reg...

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Detalles Bibliográficos
Autores principales:	Chen, Taiqiu, Lin, Youxi, Wu, Zizhao, Shi, Huihong, Hu, Wenjun, Li, Shaoguang, Que, Yichen, Qiu, Jincheng, Li, Pengfei, Qiu, Xianjian, Liang, Tongzhou, Wang, Xudong, Gao, Bo, Zhou, Hang, Deng, Zhihuai, Chen, Yanbo, Zhu, Yuanxin, Peng, Yan, Liang, Anjing, Gao, Wenjie, Huang, Dongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338732/ https://www.ncbi.nlm.nih.gov/pubmed/35915608 http://dx.doi.org/10.1155/2022/9684062

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