Effects of bone morphogenetic protein 4 on TGF-β1-induced cell proliferation, apoptosis, activation and differentiation in mouse lung fibroblasts via ERK/p38 MAPK signaling pathway

Fibroblasts, in particular myofibroblasts, are the critical effector cells in idiopathic pulmonary fibrosis (IPF), a deadly lung disease characterized by abnormal lung remodeling and the formation of “fibroblastic foci”. Aberrant activation of TGF-β1 is frequently encountered and promotes fibroblast...

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Detalles Bibliográficos
Autores principales: Cai, Zhou, Guo, Hua, Qian, Jing, Liu, Wei, Li, Yuanyuan, Yuan, Liang, Zhou, You, Lin, Ran, Xie, Xiaohui, Yang, Qiong, Wu, Guoying, Li, Qiongqiong, Zhao, Li, Liu, Fei, Wang, Jian, Lu, Wenju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338752/
https://www.ncbi.nlm.nih.gov/pubmed/35915750
http://dx.doi.org/10.7717/peerj.13775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338752/
https://www.ncbi.nlm.nih.gov/pubmed/35915750
http://dx.doi.org/10.7717/peerj.13775

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