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Effects of bone morphogenetic protein 4 on TGF-β1-induced cell proliferation, apoptosis, activation and differentiation in mouse lung fibroblasts via ERK/p38 MAPK signaling pathway
Fibroblasts, in particular myofibroblasts, are the critical effector cells in idiopathic pulmonary fibrosis (IPF), a deadly lung disease characterized by abnormal lung remodeling and the formation of “fibroblastic foci”. Aberrant activation of TGF-β1 is frequently encountered and promotes fibroblast...
Autores principales: | Cai, Zhou, Guo, Hua, Qian, Jing, Liu, Wei, Li, Yuanyuan, Yuan, Liang, Zhou, You, Lin, Ran, Xie, Xiaohui, Yang, Qiong, Wu, Guoying, Li, Qiongqiong, Zhao, Li, Liu, Fei, Wang, Jian, Lu, Wenju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338752/ https://www.ncbi.nlm.nih.gov/pubmed/35915750 http://dx.doi.org/10.7717/peerj.13775 |
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