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Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis

In order to explore the clinical efficacy of DOTATATE imaging combined with CGA and BSP in the diagnosis of bone metastasis in patients with NENs, a total of 100 NEN patients treated in our hospital from January 2021 to January 2022 were analyzed. All patients are divided into bone metastasis group...

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Autores principales: Lei, Lei, Du, Tao, Yang, Jianbo, Cai, Liang, Liu, Huipan, Chen, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338844/
https://www.ncbi.nlm.nih.gov/pubmed/35915791
http://dx.doi.org/10.1155/2022/6279826
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author Lei, Lei
Du, Tao
Yang, Jianbo
Cai, Liang
Liu, Huipan
Chen, Yue
author_facet Lei, Lei
Du, Tao
Yang, Jianbo
Cai, Liang
Liu, Huipan
Chen, Yue
author_sort Lei, Lei
collection PubMed
description In order to explore the clinical efficacy of DOTATATE imaging combined with CGA and BSP in the diagnosis of bone metastasis in patients with NENs, a total of 100 NEN patients treated in our hospital from January 2021 to January 2022 were analyzed. All patients are divided into bone metastasis group and nonmetastasis group according to pathological examination results. The differences of DOTATATE imaging, CGA, and BSP are compared, and ROC curves are obtained to analyze the clinical efficacy of the three indicators in single application and combined diagnosis. The results show that AUC, sensitivity, and specificity of DOTATATE, BSP, and CGA combined diagnosis are higher than those of single diagnosis (P < 0.05). It is clearly evident that DOTATATE test, BSP, and CGA can obtain accurate results in the diagnosis of bone metastasis in NEN patients, and those combined diagnosis can improve the diagnostic efficiency.
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spelling pubmed-93388442022-07-31 Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis Lei, Lei Du, Tao Yang, Jianbo Cai, Liang Liu, Huipan Chen, Yue Biomed Res Int Research Article In order to explore the clinical efficacy of DOTATATE imaging combined with CGA and BSP in the diagnosis of bone metastasis in patients with NENs, a total of 100 NEN patients treated in our hospital from January 2021 to January 2022 were analyzed. All patients are divided into bone metastasis group and nonmetastasis group according to pathological examination results. The differences of DOTATATE imaging, CGA, and BSP are compared, and ROC curves are obtained to analyze the clinical efficacy of the three indicators in single application and combined diagnosis. The results show that AUC, sensitivity, and specificity of DOTATATE, BSP, and CGA combined diagnosis are higher than those of single diagnosis (P < 0.05). It is clearly evident that DOTATATE test, BSP, and CGA can obtain accurate results in the diagnosis of bone metastasis in NEN patients, and those combined diagnosis can improve the diagnostic efficiency. Hindawi 2022-07-23 /pmc/articles/PMC9338844/ /pubmed/35915791 http://dx.doi.org/10.1155/2022/6279826 Text en Copyright © 2022 Lei Lei et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Lei, Lei
Du, Tao
Yang, Jianbo
Cai, Liang
Liu, Huipan
Chen, Yue
Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis
title Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis
title_full Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis
title_fullStr Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis
title_full_unstemmed Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis
title_short Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis
title_sort analysis of the diagnostic efficacy of dotatate imaging combined with cga and bsp detection mode for nen patients with bone metastasis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338844/
https://www.ncbi.nlm.nih.gov/pubmed/35915791
http://dx.doi.org/10.1155/2022/6279826
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