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Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis
In order to explore the clinical efficacy of DOTATATE imaging combined with CGA and BSP in the diagnosis of bone metastasis in patients with NENs, a total of 100 NEN patients treated in our hospital from January 2021 to January 2022 were analyzed. All patients are divided into bone metastasis group...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338844/ https://www.ncbi.nlm.nih.gov/pubmed/35915791 http://dx.doi.org/10.1155/2022/6279826 |
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author | Lei, Lei Du, Tao Yang, Jianbo Cai, Liang Liu, Huipan Chen, Yue |
author_facet | Lei, Lei Du, Tao Yang, Jianbo Cai, Liang Liu, Huipan Chen, Yue |
author_sort | Lei, Lei |
collection | PubMed |
description | In order to explore the clinical efficacy of DOTATATE imaging combined with CGA and BSP in the diagnosis of bone metastasis in patients with NENs, a total of 100 NEN patients treated in our hospital from January 2021 to January 2022 were analyzed. All patients are divided into bone metastasis group and nonmetastasis group according to pathological examination results. The differences of DOTATATE imaging, CGA, and BSP are compared, and ROC curves are obtained to analyze the clinical efficacy of the three indicators in single application and combined diagnosis. The results show that AUC, sensitivity, and specificity of DOTATATE, BSP, and CGA combined diagnosis are higher than those of single diagnosis (P < 0.05). It is clearly evident that DOTATATE test, BSP, and CGA can obtain accurate results in the diagnosis of bone metastasis in NEN patients, and those combined diagnosis can improve the diagnostic efficiency. |
format | Online Article Text |
id | pubmed-9338844 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-93388442022-07-31 Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis Lei, Lei Du, Tao Yang, Jianbo Cai, Liang Liu, Huipan Chen, Yue Biomed Res Int Research Article In order to explore the clinical efficacy of DOTATATE imaging combined with CGA and BSP in the diagnosis of bone metastasis in patients with NENs, a total of 100 NEN patients treated in our hospital from January 2021 to January 2022 were analyzed. All patients are divided into bone metastasis group and nonmetastasis group according to pathological examination results. The differences of DOTATATE imaging, CGA, and BSP are compared, and ROC curves are obtained to analyze the clinical efficacy of the three indicators in single application and combined diagnosis. The results show that AUC, sensitivity, and specificity of DOTATATE, BSP, and CGA combined diagnosis are higher than those of single diagnosis (P < 0.05). It is clearly evident that DOTATATE test, BSP, and CGA can obtain accurate results in the diagnosis of bone metastasis in NEN patients, and those combined diagnosis can improve the diagnostic efficiency. Hindawi 2022-07-23 /pmc/articles/PMC9338844/ /pubmed/35915791 http://dx.doi.org/10.1155/2022/6279826 Text en Copyright © 2022 Lei Lei et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Lei, Lei Du, Tao Yang, Jianbo Cai, Liang Liu, Huipan Chen, Yue Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis |
title | Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis |
title_full | Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis |
title_fullStr | Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis |
title_full_unstemmed | Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis |
title_short | Analysis of the Diagnostic Efficacy of DOTATATE Imaging Combined with CGA and BSP Detection Mode for NEN Patients with Bone Metastasis |
title_sort | analysis of the diagnostic efficacy of dotatate imaging combined with cga and bsp detection mode for nen patients with bone metastasis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338844/ https://www.ncbi.nlm.nih.gov/pubmed/35915791 http://dx.doi.org/10.1155/2022/6279826 |
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