mTOR Modulates the Endoplasmic Reticulum Stress-Induced CD4(+) T Cell Apoptosis Mediated by ROS in Septic Immunosuppression

INTRODUCTION: When sepsis attacks the body, the excessive reactive oxygen species (ROS) production can result to endoplasmic reticulum stress (ERS) and eventually cause lymphocyte apoptosis. The mammalian target of rapamycin (mTOR) is essential for regulating lymphocyte apoptosis; we hypothesized th...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Chen, Jianwei, Bai, Guangxu, Han, Wen, Guo, Ran, Cui, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338879/
https://www.ncbi.nlm.nih.gov/pubmed/35915740
http://dx.doi.org/10.1155/2022/6077570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338879/
https://www.ncbi.nlm.nih.gov/pubmed/35915740
http://dx.doi.org/10.1155/2022/6077570

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