RNA-binding protein RBM3 intrinsically suppresses lung innate lymphoid cell activation and inflammation partially through CysLT1R

Innate lymphoid cells (ILC) promote lung inflammation in asthma through cytokine production. RNA-binding proteins (RBPs) are critical post-transcriptional regulators, although less is known about RBPs in ILC biology. Here, we demonstrate that RNA-binding motif 3 (RBM3) is highly expressed in lung IL...

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Detalles Bibliográficos
Autores principales: Badrani, Jana H., Strohm, Allyssa N., Lacasa, Lee, Civello, Blake, Cavagnero, Kellen, Haung, Yung-An, Amadeo, Michael, Naji, Luay H., Lund, Sean J., Leng, Anthea, Kim, Hyojoung, Baum, Rachel E., Khorram, Naseem, Mondal, Monalisa, Seumois, Grégory, Pilotte, Julie, Vanderklish, Peter W., McGee, Heather M., Doherty, Taylor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338970/
https://www.ncbi.nlm.nih.gov/pubmed/35908044
http://dx.doi.org/10.1038/s41467-022-32176-5

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