Structural basis for assembly and disassembly of the IGF/IGFBP/ALS ternary complex

Insulin-like growth factors (IGFs) have pleiotropic roles in embryonic and postnatal growth and differentiation. Most serum IGFs are bound in a ternary complex with IGF-binding protein 3 (IGFBP3) and acid-labile subunit (ALS), extending the serum half-life of IGFs and regulating their availability....

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Detalles Bibliográficos
Autores principales: Kim, Hyojin, Fu, Yaoyao, Hong, Ho Jeong, Lee, Seong-Gyu, Lee, Dong Sun, Kim, Ho Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338993/
https://www.ncbi.nlm.nih.gov/pubmed/35907924
http://dx.doi.org/10.1038/s41467-022-32214-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338993/
https://www.ncbi.nlm.nih.gov/pubmed/35907924
http://dx.doi.org/10.1038/s41467-022-32214-2

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