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Impact of vaccination and the omicron variant on COVID-19 severity in pregnant women

We compared the clinical course of pregnant women with coronavirus disease 2019 (COVID-19) before and after the emergence of the omicron variant and based on vaccination status. We retrospectively reviewed the electronic medical charts of 224 patients and 82 deliveries from November 1, 2020, to Marc...

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Autores principales: Kim, Haemin, Kim, Hyo-Shin, Kim, Hyun Mi, Kim, Mi Ju, Kwon, Ki Tae, Cha, Hyun-Hwa, Seong, Won Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339152/
https://www.ncbi.nlm.nih.gov/pubmed/35921943
http://dx.doi.org/10.1016/j.ajic.2022.07.023
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author Kim, Haemin
Kim, Hyo-Shin
Kim, Hyun Mi
Kim, Mi Ju
Kwon, Ki Tae
Cha, Hyun-Hwa
Seong, Won Joon
author_facet Kim, Haemin
Kim, Hyo-Shin
Kim, Hyun Mi
Kim, Mi Ju
Kwon, Ki Tae
Cha, Hyun-Hwa
Seong, Won Joon
author_sort Kim, Haemin
collection PubMed
description We compared the clinical course of pregnant women with coronavirus disease 2019 (COVID-19) before and after the emergence of the omicron variant and based on vaccination status. We retrospectively reviewed the electronic medical charts of 224 patients and 82 deliveries from November 1, 2020, to March 7, 2022; of these, 42% were diagnosed during the omicron dominance period. Disease severity and morbidity of COVID-19 were significantly decreased during the omicron era. The vaccination rates among the patients were higher after omicron emergence (31.9%) than before (6.9%). Overall, 4.1% and 25% of patients had severe symptoms, and 2.6% and 16.2% required oxygen therapy in the vaccination and non-vaccination groups, respectively. Overall, patients had a more favorable clinical course in the omicron era; moreover, vaccinated patients were better protected than non-vaccinated patients, indicating the importance of vaccination against COVID-19.
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spelling pubmed-93391522022-08-01 Impact of vaccination and the omicron variant on COVID-19 severity in pregnant women Kim, Haemin Kim, Hyo-Shin Kim, Hyun Mi Kim, Mi Ju Kwon, Ki Tae Cha, Hyun-Hwa Seong, Won Joon Am J Infect Control Brief Report We compared the clinical course of pregnant women with coronavirus disease 2019 (COVID-19) before and after the emergence of the omicron variant and based on vaccination status. We retrospectively reviewed the electronic medical charts of 224 patients and 82 deliveries from November 1, 2020, to March 7, 2022; of these, 42% were diagnosed during the omicron dominance period. Disease severity and morbidity of COVID-19 were significantly decreased during the omicron era. The vaccination rates among the patients were higher after omicron emergence (31.9%) than before (6.9%). Overall, 4.1% and 25% of patients had severe symptoms, and 2.6% and 16.2% required oxygen therapy in the vaccination and non-vaccination groups, respectively. Overall, patients had a more favorable clinical course in the omicron era; moreover, vaccinated patients were better protected than non-vaccinated patients, indicating the importance of vaccination against COVID-19. Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. 2023-03 2022-07-31 /pmc/articles/PMC9339152/ /pubmed/35921943 http://dx.doi.org/10.1016/j.ajic.2022.07.023 Text en © 2022 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Brief Report
Kim, Haemin
Kim, Hyo-Shin
Kim, Hyun Mi
Kim, Mi Ju
Kwon, Ki Tae
Cha, Hyun-Hwa
Seong, Won Joon
Impact of vaccination and the omicron variant on COVID-19 severity in pregnant women
title Impact of vaccination and the omicron variant on COVID-19 severity in pregnant women
title_full Impact of vaccination and the omicron variant on COVID-19 severity in pregnant women
title_fullStr Impact of vaccination and the omicron variant on COVID-19 severity in pregnant women
title_full_unstemmed Impact of vaccination and the omicron variant on COVID-19 severity in pregnant women
title_short Impact of vaccination and the omicron variant on COVID-19 severity in pregnant women
title_sort impact of vaccination and the omicron variant on covid-19 severity in pregnant women
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339152/
https://www.ncbi.nlm.nih.gov/pubmed/35921943
http://dx.doi.org/10.1016/j.ajic.2022.07.023
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