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Deficient DNA base-excision repair in the forebrain leads to a sex-specific anxiety-like phenotype in mice
BACKGROUND: Neuropsychiatric disorders, such as schizophrenia (SZ) and autism spectrum disorder (ASD), are common, multi-factorial and multi-symptomatic disorders. Ample evidence implicates oxidative stress, deficient repair of oxidative DNA lesions and DNA damage in the development of these disorde...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339204/ https://www.ncbi.nlm.nih.gov/pubmed/35907861 http://dx.doi.org/10.1186/s12915-022-01377-1 |