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Deficient DNA base-excision repair in the forebrain leads to a sex-specific anxiety-like phenotype in mice

BACKGROUND: Neuropsychiatric disorders, such as schizophrenia (SZ) and autism spectrum disorder (ASD), are common, multi-factorial and multi-symptomatic disorders. Ample evidence implicates oxidative stress, deficient repair of oxidative DNA lesions and DNA damage in the development of these disorde...

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Detalles Bibliográficos
Autores principales:	Mueller, Flavia S., Amport, René, Notter, Tina, Schalbetter, Sina M., Lin, Han-Yu, Garajova, Zuzana, Amini, Parisa, Weber-Stadlbauer, Ulrike, Markkanen, Enni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339204/ https://www.ncbi.nlm.nih.gov/pubmed/35907861 http://dx.doi.org/10.1186/s12915-022-01377-1

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