Increased gene dosage and mRNA expression from chromosomal duplications in Caenorhabditis elegans

Isolation of copy number variations and chromosomal duplications at high frequency in the laboratory suggested that Caenorhabditis elegans tolerates increased gene dosage. Here, we addressed if a general dosage compensation mechanism acts at the level of mRNA expression in C. elegans. We characteriz...

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Detalles Bibliográficos
Autores principales: Ragipani, Bhavana, Albritton, Sarah Elizabeth, Morao, Ana Karina, Mesquita, Diogo, Kramer, Maxwell, Ercan, Sevinç
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339279/
https://www.ncbi.nlm.nih.gov/pubmed/35731207
http://dx.doi.org/10.1093/g3journal/jkac151

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