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Stepwise differentiation of functional pancreatic β cells from human pluripotent stem cells

Pancreatic β cells differentiated from stem cells provide promise for cell replacement therapy of diabetes. Human pluripotent stem cells could be differentiated into definitive endoderm, followed by pancreatic progenitors, and then subjected to endocrinal differentiation and maturation in a stepwise...

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Detalles Bibliográficos
Autores principales: Jin, Wenwen, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339430/
https://www.ncbi.nlm.nih.gov/pubmed/35909206
http://dx.doi.org/10.1186/s13619-022-00125-8