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Cryptotanshinone suppresses tumorigenesis by inhibiting lipogenesis and promoting reactive oxygen species production in KRAS-activated pancreatic cancer cells

Pyruvate dehydrogenase kinase 4 (PDK4) is an important regulator of energy metabolism. Previously, knockdown of PDK4 by specific small interfering RNAs (siRNAs) have been shown to suppress the expression of Kirsten rat sarcoma viral oncogene homolog (KRAS) and the growth of lung and colorectal cance...

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Detalles Bibliográficos
Autores principales:	Terado, Tokio, Kim, Chul Jang, Ushio, Akiyo, Minami, Kahori, Tambe, Yukihiro, Kageyama, Susumu, Kawauchi, Akihiro, Tsunoda, Toshiyuki, Shirasawa, Senji, Tanaka, Hiroyuki, Inoue, Hirokazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339489/ https://www.ncbi.nlm.nih.gov/pubmed/35894141 http://dx.doi.org/10.3892/ijo.2022.5398

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