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Cardiomyocyte-specific knockout of ADAM17 ameliorates left ventricular remodeling and function in diabetic cardiomyopathy of mice

Angiotensin-converting enzyme 2 (ACE2) has proven beneficial in attenuating diabetic cardiomyopathy (DCM) but has been found to be a substrate of a disintegrin and metalloprotease protein-17 (ADAM17). However, whether ADAM17 plays a role in the pathogenesis and intervention of DCM is obscure. In thi...

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Detalles Bibliográficos
Autores principales:	Xue, Fei, Cheng, Jing, Liu, Yanping, Cheng, Cheng, Zhang, Meng, Sui, Wenhai, Chen, Wenqiang, Hao, Panpan, Zhang, Yun, Zhang, Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339545/ https://www.ncbi.nlm.nih.gov/pubmed/35909160 http://dx.doi.org/10.1038/s41392-022-01054-3

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