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Targeting mAKAPβ Expression as a Therapeutic Approach for Ischemic Cardiomyopathy

Ischemic cardiomyopathy is a leading cause of death and an unmet clinical need. Adeno-associated virus (AAV) gene-based therapies hold great promise for treating and preventing heart failure. Previously we showed that muscle A-kinase Anchoring Protein β (mAKAPβ, AKAP6β), a scaffold protein that orga...

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Detalles Bibliográficos
Autores principales: Martinez, Eliana C., Li, Jinliang, Ataam, Jennifer Arthur, Tokarski, Kristin, Thakur, Hrishikesh, Karakikes, Ioannis, Dodge-Kafka, Kimberly, Kapiloff, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339585/
https://www.ncbi.nlm.nih.gov/pubmed/35102273
http://dx.doi.org/10.1038/s41434-022-00321-w