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Absence of Bacteria Permits Fungal Gut-To-Brain Translocation and Invasion in Germfree Mice but Ageing Alone Does Not Drive Pathobiont Expansion in Conventionally Raised Mice

Age-associated changes in the structure of the intestinal microbiome and in its interaction with the brain via the gut-brain axis are increasingly being implicated in neurological and neurodegenerative diseases. Intestinal microbial dysbiosis and translocation of microbes and microbial products incl...

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Detalles Bibliográficos
Autores principales: Parker, Aimée, James, Steve A., Purse, Catherine, Brion, Arlaine, Goldson, Andrew, Telatin, Andrea, Baker, David, Carding, Simon R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9339909/
https://www.ncbi.nlm.nih.gov/pubmed/35923548
http://dx.doi.org/10.3389/fnagi.2022.828429