A case of improved quality of life in a patient with inoperable pancreatic cancer after repeated RFA()

Radiofrequency ablation (RFA) has widespread popularity due to its immune-modulation effects in many cancers. Optimal settings to apply RFA in pancreatic cancer, in which the advanced stage of the tumor at the diagnosis makes various therapeutic approaches fail, are still demanding. We report the ca...

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Autores principales: Toria, Nino, Kikodze, Nino, Janikashvili, Nona, Pantsulaia, Ia, Mizandari, Malkhaz, Chikovani, Tinatin, Habib, Nagy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340145/
https://www.ncbi.nlm.nih.gov/pubmed/35923339
http://dx.doi.org/10.1016/j.radcr.2022.07.017
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author Toria, Nino
Kikodze, Nino
Janikashvili, Nona
Pantsulaia, Ia
Mizandari, Malkhaz
Chikovani, Tinatin
Habib, Nagy
author_facet Toria, Nino
Kikodze, Nino
Janikashvili, Nona
Pantsulaia, Ia
Mizandari, Malkhaz
Chikovani, Tinatin
Habib, Nagy
author_sort Toria, Nino
collection PubMed
description Radiofrequency ablation (RFA) has widespread popularity due to its immune-modulation effects in many cancers. Optimal settings to apply RFA in pancreatic cancer, in which the advanced stage of the tumor at the diagnosis makes various therapeutic approaches fail, are still demanding. We report the case of a patient with unresectable pancreatic cancer in which 3 repetitive RFA has been applied over a period of 3 months. Results revealed an improvement in the patient's clinical condition associated with the reduced incidence of CD4+CD45RO+ T lymphocytes and declined TGF-β level in serum. The good quality of life and disease-free survival were maintained for the next months. Booster application of RFA procedure might be a promising option to improve the quality of life in pancreatic cancer patients.
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spelling pubmed-93401452022-08-02 A case of improved quality of life in a patient with inoperable pancreatic cancer after repeated RFA() Toria, Nino Kikodze, Nino Janikashvili, Nona Pantsulaia, Ia Mizandari, Malkhaz Chikovani, Tinatin Habib, Nagy Radiol Case Rep Case Report Radiofrequency ablation (RFA) has widespread popularity due to its immune-modulation effects in many cancers. Optimal settings to apply RFA in pancreatic cancer, in which the advanced stage of the tumor at the diagnosis makes various therapeutic approaches fail, are still demanding. We report the case of a patient with unresectable pancreatic cancer in which 3 repetitive RFA has been applied over a period of 3 months. Results revealed an improvement in the patient's clinical condition associated with the reduced incidence of CD4+CD45RO+ T lymphocytes and declined TGF-β level in serum. The good quality of life and disease-free survival were maintained for the next months. Booster application of RFA procedure might be a promising option to improve the quality of life in pancreatic cancer patients. Elsevier 2022-07-29 /pmc/articles/PMC9340145/ /pubmed/35923339 http://dx.doi.org/10.1016/j.radcr.2022.07.017 Text en © 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Toria, Nino
Kikodze, Nino
Janikashvili, Nona
Pantsulaia, Ia
Mizandari, Malkhaz
Chikovani, Tinatin
Habib, Nagy
A case of improved quality of life in a patient with inoperable pancreatic cancer after repeated RFA()
title A case of improved quality of life in a patient with inoperable pancreatic cancer after repeated RFA()
title_full A case of improved quality of life in a patient with inoperable pancreatic cancer after repeated RFA()
title_fullStr A case of improved quality of life in a patient with inoperable pancreatic cancer after repeated RFA()
title_full_unstemmed A case of improved quality of life in a patient with inoperable pancreatic cancer after repeated RFA()
title_short A case of improved quality of life in a patient with inoperable pancreatic cancer after repeated RFA()
title_sort case of improved quality of life in a patient with inoperable pancreatic cancer after repeated rfa()
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340145/
https://www.ncbi.nlm.nih.gov/pubmed/35923339
http://dx.doi.org/10.1016/j.radcr.2022.07.017
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