Model-Informed Drug Development of New Cefoperazone Sodium and Sulbactam Sodium Combination (3:1): Pharmacokinetic/Pharmacodynamic Analysis and Antibacterial Efficacy Against Enterobacteriaceae

Objective: Cefoperazone/sulbactam is a commonly used antibiotic combination against the extended-spectrum beta-lactamases (ESBLs)-producing bacteria. The objective of this study was to evaluate the efficacy of a new cefoperazone/sulbactam combination (3:1) for Enterobacteriaceae infection via model-...

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Detalles Bibliográficos
Autores principales: Ji, Xi-Wei, Zhu, Xiao, Li, Yun, Xue, Feng, Kuan, Isabelle Hui San, He, Qing-Feng, Meng, Xiang-Rui, Xiang, Xiao-Qiang, Cui, Yi-Min, Zheng, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340253/
https://www.ncbi.nlm.nih.gov/pubmed/35924047
http://dx.doi.org/10.3389/fphar.2022.856792

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