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Population pharmacokinetics model for escitalopram in Chinese psychiatric patients: effect of CYP2C19 and age
Objective: To establish a population pharmacokinetic model in Chinese psychiatric patients to characterize escitalopram pharmacokinetic profile to identify factors influencing drug exposure, and through simulation to compare the results with the established therapeutic reference range. Methods: Demo...
Autores principales: | Liu, Shujing, Xiao, Tao, Huang, Shanqing, Li, Xiaolin, Kong, Wan, Yang, Ye, Zhang, Zi, Ni, Xiaojia, Lu, Haoyang, Zhang, Ming, Shang, Dewei, Wen, Yuguan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340256/ https://www.ncbi.nlm.nih.gov/pubmed/35924062 http://dx.doi.org/10.3389/fphar.2022.964758 |
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