Impairment of RAD17 Functions by miR-506-3p as a Novel Synthetic Lethal Approach Targeting DNA Repair Pathways in Ovarian Cancer

Epithelial ovarian cancer (EOC) remains the most lethal gynecological cancer and development of chemo-resistance is a major factor in disease relapse. Homologous recombination (HR) is a critical pathway for DNA double strand break repair and its deficiency is associated to a better response to DNA d...

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Detalles Bibliográficos
Autores principales: Bagnoli, Marina, Nicoletti, Roberta, Valitutti, Monica, Rizzo, Andrea, Napoli, Alessandra, Montalvão De Azevedo, Rafaela, Tomassetti, Antonella, Mezzanzanica, Delia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340372/
https://www.ncbi.nlm.nih.gov/pubmed/35924161
http://dx.doi.org/10.3389/fonc.2022.923508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340372/
https://www.ncbi.nlm.nih.gov/pubmed/35924161
http://dx.doi.org/10.3389/fonc.2022.923508

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