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Efficacy and safety of selpercatinib in Chinese patients with advanced RET fusion-positive non-small-cell lung cancer: a phase II clinical trial (LIBRETTO-321)

INTRODUCTION: Oncogenic alterations in RET occur in 1–2% of non-small-cell lung cancers (NSCLCs). The efficacy and safety of the first-in-class, highly selective, and potent RET inhibitor selpercatinib in Chinese patients with RET fusion-positive NSCLC remains unknown. METHODS: In this open-label, m...

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Detalles Bibliográficos
Autores principales:	Lu, Shun, Cheng, Ying, Huang, Dingzhi, Sun, Yuping, Wu, Lin, Zhou, Chengzhi, Guo, Ye, Shao, Jingxin, Zhang, Wanli, Zhou, Jianying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340421/ https://www.ncbi.nlm.nih.gov/pubmed/35923928 http://dx.doi.org/10.1177/17588359221105020

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