A heterotypic assembly mechanism regulates CHIP E3 ligase activity

CHIP (C‐terminus of Hsc70‐interacting protein) and its worm ortholog CHN‐1 are E3 ubiquitin ligases that link the chaperone system with the ubiquitin‐proteasome system (UPS). CHN‐1 can cooperate with UFD‐2, another E3 ligase, to accelerate ubiquitin chain formation; however, the basis for the high p...

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Detalles Bibliográficos
Autores principales: Das, Aniruddha, Thapa, Pankaj, Santiago, Ulises, Shanmugam, Nilesh, Banasiak, Katarzyna, Dąbrowska, Katarzyna, Nolte, Hendrik, Szulc, Natalia A, Gathungu, Rose M, Cysewski, Dominik, Krüger, Marcus, Dadlez, Michał, Nowotny, Marcin, Camacho, Carlos J, Hoppe, Thorsten, Pokrzywa, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340540/
https://www.ncbi.nlm.nih.gov/pubmed/35762422
http://dx.doi.org/10.15252/embj.2021109566

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