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ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning

Precise vascular patterning is crucial for normal growth and development. The ERG transcription factor drives Delta-like ligand 4 (DLL4)/Notch signalling and is thought to act as a pivotal regulator of endothelial cell (EC) dynamics and developmental angiogenesis. However, molecular regulation of ER...

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Detalles Bibliográficos
Autores principales: D'Amico, Gabriela, Fernandez, Isabelle, Gómez-Escudero, Jesús, Kim, Hyojin, Maniati, Eleni, Azman, Muhammad Syahmi, Mardakheh, Faraz K., Serrels, Bryan, Serrels, Alan, Parsons, Maddy, Squire, Anthony, Birdsey, Graeme M., Randi, Anna M., Bolado-Carrancio, Alfonso, Gangeswaran, Rathi, Reynolds, Louise E., Bodrug, Natalia, Wang, Yaohe, Wang, Jun, Meier, Pascal, Hodivala-Dilke, Kairbaan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340553/
https://www.ncbi.nlm.nih.gov/pubmed/35723257
http://dx.doi.org/10.1242/dev.200528