Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency

Vitamin B12 deficiency is a multifactorial condition, with a wide range of clinical presentations from mild to severe anemia and anemia-related neurological deficits. Hemolysis is a unique cause but has increasingly been recognized lately as a possible B12 deficiency presentation. Our patient presen...

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Autores principales: Abdalla, ELMustafa, Al-Sadi, Anas, Fadul, Abdalla, Ahmed, Ahmed H, Musa, Muzamil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340670/
https://www.ncbi.nlm.nih.gov/pubmed/35923488
http://dx.doi.org/10.7759/cureus.26507
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author Abdalla, ELMustafa
Al-Sadi, Anas
Fadul, Abdalla
Ahmed, Ahmed H
Musa, Muzamil
author_facet Abdalla, ELMustafa
Al-Sadi, Anas
Fadul, Abdalla
Ahmed, Ahmed H
Musa, Muzamil
author_sort Abdalla, ELMustafa
collection PubMed
description Vitamin B12 deficiency is a multifactorial condition, with a wide range of clinical presentations from mild to severe anemia and anemia-related neurological deficits. Hemolysis is a unique cause but has increasingly been recognized lately as a possible B12 deficiency presentation. Our patient presented with hemolytic anemia, for which extensive workup has excluded the common hemolysis etiologies. Therefore, it was attributed to B12 deficiency and improved significantly after treatment. Our case highlights the significance of this unusual presentation and its clinical implementation.
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spelling pubmed-93406702022-08-02 Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency Abdalla, ELMustafa Al-Sadi, Anas Fadul, Abdalla Ahmed, Ahmed H Musa, Muzamil Cureus Internal Medicine Vitamin B12 deficiency is a multifactorial condition, with a wide range of clinical presentations from mild to severe anemia and anemia-related neurological deficits. Hemolysis is a unique cause but has increasingly been recognized lately as a possible B12 deficiency presentation. Our patient presented with hemolytic anemia, for which extensive workup has excluded the common hemolysis etiologies. Therefore, it was attributed to B12 deficiency and improved significantly after treatment. Our case highlights the significance of this unusual presentation and its clinical implementation. Cureus 2022-07-02 /pmc/articles/PMC9340670/ /pubmed/35923488 http://dx.doi.org/10.7759/cureus.26507 Text en Copyright © 2022, Abdalla et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Abdalla, ELMustafa
Al-Sadi, Anas
Fadul, Abdalla
Ahmed, Ahmed H
Musa, Muzamil
Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency
title Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency
title_full Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency
title_fullStr Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency
title_full_unstemmed Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency
title_short Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency
title_sort non-immune intravascular hemolytic anemia, an unusual presentation of severe vitamin b-12 deficiency
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340670/
https://www.ncbi.nlm.nih.gov/pubmed/35923488
http://dx.doi.org/10.7759/cureus.26507
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