APOE interacts with ACE2 inhibiting SARS-CoV-2 cellular entry and inflammation in COVID-19 patients

Apolipoprotein E (APOE) plays a pivotal role in lipid including cholesterol metabolism. The APOE ε4 (APOE4) allele is a major genetic risk factor for Alzheimer’s and cardiovascular diseases. Although APOE has recently been associated with increased susceptibility to infections of several viruses, wh...

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Detalles Bibliográficos
Autores principales: Zhang, Hongsheng, Shao, Lin, Lin, Zhihao, Long, Quan-Xin, Yuan, Huilong, Cai, Lujian, Jiang, Guangtong, Guo, Xiaoyi, Yang, Renzhi, Zhang, Zepeng, Zhang, Bingchang, Liu, Fan, Li, Zhiyong, Ma, Qilin, Zhang, Yun-Wu, Huang, Ai-Long, Wang, Zhanxiang, Zhao, Yingjun, Xu, Huaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340718/
https://www.ncbi.nlm.nih.gov/pubmed/35915083
http://dx.doi.org/10.1038/s41392-022-01118-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340718/
https://www.ncbi.nlm.nih.gov/pubmed/35915083
http://dx.doi.org/10.1038/s41392-022-01118-4

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