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Survival status and predictor of mortality among adult stroke patients in Saint Paul’s hospital millennium medical college, Addis Ababa, Ethiopia

OBJECTIVE: In Africa, there is up to 316 per 100,000 annual incidence rate of stroke, a prevalence of up to 1460 per 100,000, and a 3-year mortality rate higher than 80%. The incidence of stroke mortality in Ethiopia is 19.2%. Stroke is a major cause of disability and death worldwide. Early mortalit...

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Autores principales: Sahle Adeba, Tadesse, Mekonen, Hussen, Alemu, Tsion, Alate, Tamrat, Melis, Tamirat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340903/
https://www.ncbi.nlm.nih.gov/pubmed/35924142
http://dx.doi.org/10.1177/20503121221112483
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author Sahle Adeba, Tadesse
Mekonen, Hussen
Alemu, Tsion
Alate, Tamrat
Melis, Tamirat
author_facet Sahle Adeba, Tadesse
Mekonen, Hussen
Alemu, Tsion
Alate, Tamrat
Melis, Tamirat
author_sort Sahle Adeba, Tadesse
collection PubMed
description OBJECTIVE: In Africa, there is up to 316 per 100,000 annual incidence rate of stroke, a prevalence of up to 1460 per 100,000, and a 3-year mortality rate higher than 80%. The incidence of stroke mortality in Ethiopia is 19.2%. Stroke is a major cause of disability and death worldwide. Early mortality in-hospital and deprived functional outcomes are common in acute stroke. This study aims to assess survival status and predictors of mortality among adult stroke patients. METHODS: Institution-based retrospective cohort was conducted on patients who were admitted to Saint Paul’s Hospital Millennium Medical College. A simple random sampling technique was used. Bivariate and multivariable cox regression analysis were used to identify predictors of stroke mortality. For multivariable cox regression analysis statistically, significance was declared at p-value <0.05 and 95% CI. RESULTS: A total of 251 adult stroke patient charts were included in the study. The overall Kaplan–Meier estimate showed that the probability of in-hospital stroke patients’ survival on the 41st day was nearly 50%. In this study, 77 (30.7%) of the study participants died. Decreased Glasgow Coma Scale (GCS) with adjusted hazard ratio (AHR) 4.26 (95% CI: 2.25–8.07) and p-value ⩽ 0.01 and presence of pneumonia with AHR 3.05 (95% CI: 1.29–7.21) and p-value ⩽ 0.01 are the predictor of mortality. CONCLUSION: The probability of survival relatively falls as follow-up time increases. The overall incidence of mortality among adult stroke patients was high. The decreased GCS and the presence of pneumonia are predictors of mortality among adult stroke patients.
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spelling pubmed-93409032022-08-02 Survival status and predictor of mortality among adult stroke patients in Saint Paul’s hospital millennium medical college, Addis Ababa, Ethiopia Sahle Adeba, Tadesse Mekonen, Hussen Alemu, Tsion Alate, Tamrat Melis, Tamirat SAGE Open Med Original Research Article OBJECTIVE: In Africa, there is up to 316 per 100,000 annual incidence rate of stroke, a prevalence of up to 1460 per 100,000, and a 3-year mortality rate higher than 80%. The incidence of stroke mortality in Ethiopia is 19.2%. Stroke is a major cause of disability and death worldwide. Early mortality in-hospital and deprived functional outcomes are common in acute stroke. This study aims to assess survival status and predictors of mortality among adult stroke patients. METHODS: Institution-based retrospective cohort was conducted on patients who were admitted to Saint Paul’s Hospital Millennium Medical College. A simple random sampling technique was used. Bivariate and multivariable cox regression analysis were used to identify predictors of stroke mortality. For multivariable cox regression analysis statistically, significance was declared at p-value <0.05 and 95% CI. RESULTS: A total of 251 adult stroke patient charts were included in the study. The overall Kaplan–Meier estimate showed that the probability of in-hospital stroke patients’ survival on the 41st day was nearly 50%. In this study, 77 (30.7%) of the study participants died. Decreased Glasgow Coma Scale (GCS) with adjusted hazard ratio (AHR) 4.26 (95% CI: 2.25–8.07) and p-value ⩽ 0.01 and presence of pneumonia with AHR 3.05 (95% CI: 1.29–7.21) and p-value ⩽ 0.01 are the predictor of mortality. CONCLUSION: The probability of survival relatively falls as follow-up time increases. The overall incidence of mortality among adult stroke patients was high. The decreased GCS and the presence of pneumonia are predictors of mortality among adult stroke patients. SAGE Publications 2022-07-30 /pmc/articles/PMC9340903/ /pubmed/35924142 http://dx.doi.org/10.1177/20503121221112483 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research Article
Sahle Adeba, Tadesse
Mekonen, Hussen
Alemu, Tsion
Alate, Tamrat
Melis, Tamirat
Survival status and predictor of mortality among adult stroke patients in Saint Paul’s hospital millennium medical college, Addis Ababa, Ethiopia
title Survival status and predictor of mortality among adult stroke patients in Saint Paul’s hospital millennium medical college, Addis Ababa, Ethiopia
title_full Survival status and predictor of mortality among adult stroke patients in Saint Paul’s hospital millennium medical college, Addis Ababa, Ethiopia
title_fullStr Survival status and predictor of mortality among adult stroke patients in Saint Paul’s hospital millennium medical college, Addis Ababa, Ethiopia
title_full_unstemmed Survival status and predictor of mortality among adult stroke patients in Saint Paul’s hospital millennium medical college, Addis Ababa, Ethiopia
title_short Survival status and predictor of mortality among adult stroke patients in Saint Paul’s hospital millennium medical college, Addis Ababa, Ethiopia
title_sort survival status and predictor of mortality among adult stroke patients in saint paul’s hospital millennium medical college, addis ababa, ethiopia
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340903/
https://www.ncbi.nlm.nih.gov/pubmed/35924142
http://dx.doi.org/10.1177/20503121221112483
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