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Long-term neuropathic pain behaviors correlate with synaptic plasticity and limbic circuit alteration: a comparative observational study in mice
Neuropathic pain has long-term consequences in affective and cognitive disturbances, suggesting the involvement of supraspinal mechanisms. In this study, we used the spared nerve injury (SNI) model to characterize the development of sensory and aversive components of neuropathic pain and to determin...
Autores principales: | Guida, Francesca, Iannotta, Monica, Misso, Gabriella, Ricciardi, Flavia, Boccella, Serena, Tirino, Virginia, Falco, Michela, Desiderio, Vincenzo, Infantino, Rosmara, Pieretti, Gorizio, de Novellis, Vito, Papaccio, Gianpaolo, Luongo, Livio, Caraglia, Michele, Maione, Sabatino |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341227/ https://www.ncbi.nlm.nih.gov/pubmed/34862336 http://dx.doi.org/10.1097/j.pain.0000000000002549 |
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