Prdm12 modulates pain-related behavior by remodeling gene expression in mature nociceptors

Prdm12 is a conserved epigenetic transcriptional regulator that displays restricted expression in nociceptors of the developing peripheral nervous system. In mice, Prdm12 is required for the development of the entire nociceptive lineage. In humans, PRDM12 mutations cause congenital insensitivity to...

Descripción completa

Detalles Bibliográficos
Autores principales: Latragna, Aurore, Sabaté San José, Alba, Tsimpos, Panagiotis, Vermeiren, Simon, Gualdani, Roberta, Chakrabarti, Sampurna, Callejo, Gerard, Desiderio, Simon, Shomroni, Orr, Sitte, Maren, Kricha, Sadia, Luypaert, Maëlle, Vanhollebeke, Benoit, Laumet, Geoffroy, Salinas, Gabriela, Smith, Ewan St. John, Ris, Laurence, Bellefroid, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341233/
https://www.ncbi.nlm.nih.gov/pubmed/34961757
http://dx.doi.org/10.1097/j.pain.0000000000002536

Ejemplares similares

Ejemplares similares