Antibody-induced pain-like behavior and bone erosion: links to subclinical inflammation, osteoclast activity, and acid-sensing ion channel 3–dependent sensitization

Several bone conditions, eg, bone cancer, osteoporosis, and rheumatoid arthritis (RA), are associated with a risk of developing persistent pain. Increased osteoclast activity is often the hallmark of these bony pathologies and not only leads to bone remodeling but is also a source of pronociceptive...

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Detalles Bibliográficos
Autores principales: Jurczak, Alexandra, Delay, Lauriane, Barbier, Julie, Simon, Nils, Krock, Emerson, Sandor, Katalin, Agalave, Nilesh M., Rudjito, Resti, Wigerblad, Gustaf, Rogóż, Katarzyna, Briat, Arnaud, Miot-Noirault, Elisabeth, Martinez-Martinez, Arisai, Brömme, Dieter, Grönwall, Caroline, Malmström, Vivianne, Klareskog, Lars, Khoury, Spiro, Ferreira, Thierry, Labrum, Bonnie, Deval, Emmanuel, Jiménez-Andrade, Juan Miguel, Marchand, Fabien, Svensson, Camilla I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341234/
https://www.ncbi.nlm.nih.gov/pubmed/34924556
http://dx.doi.org/10.1097/j.pain.0000000000002543

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