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Regulatory T Cells Function in Established Systemic Inflammation and Reverse Fatal Autoimmunity
The immunosuppressive function of regulatory T (Treg) cells is dependent on continuous expression of the transcription factor Foxp3. Foxp3 loss-of-function or induced ablation of Treg cells results in a fatal autoimmune disease featuring all known types of inflammatory responses with every manifesta...
Autores principales: | Hu, Wei, Wang, Zhong-Min, Feng, Yongqiang, Schizas, Michail, Hoyos, Beatrice E., van der Veeken, Joris, Verter, Jacob G., Bou-Puerto, Regina, Rudensky, Alexander Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341271/ https://www.ncbi.nlm.nih.gov/pubmed/34426690 http://dx.doi.org/10.1038/s41590-021-01001-4 |
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