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Targeting Impaired Nutrient Sensing via the Glycogen Synthase Kinase-3 Pathway With Therapeutic Compounds to Prevent or Treat Dementia: A Systematic Review

Background: Dementia is a global challenge with 10 million individuals being diagnosed every year. Currently, there are no established disease-modifying treatments for dementia. Impaired nutrient sensing has been implicated in the pathogenesis of dementia. Compounds that inhibit the glycogen synthas...

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Detalles Bibliográficos
Autores principales:	Matysek, Adrian, Kimmantudawage, Sumudu Perera, Feng, Lei, Maier, Andrea B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Aging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341294/ https://www.ncbi.nlm.nih.gov/pubmed/35923682 http://dx.doi.org/10.3389/fragi.2022.898853

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