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Gut bacteria interact directly with colonic mast cells in a humanized mouse model of IBS

Both mast cells and microbiota play important roles in the pathogenesis of Irritable Bowel Syndrome (IBS), however the precise mechanisms are unknown. Using microbiota-humanized IBS mouse model, we show that colonic mast cells and mast cells co-localized with neurons were higher in mice colonized wi...

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Detalles Bibliográficos
Autores principales:	Shimbori, Chiko, De Palma, Giada, Baerg, Lauren, Lu, Jun, Verdu, Elena F., Reed, David E., Vanner, Stephen, Collins, Stephen M., Bercik, Premysl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341375/ https://www.ncbi.nlm.nih.gov/pubmed/35905313 http://dx.doi.org/10.1080/19490976.2022.2105095

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