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Identifying cell state–associated alternative splicing events and their coregulation

Alternative splicing shapes the transcriptome and contributes to each cell's unique identity, but single-cell RNA sequencing (scRNA-seq) has struggled to capture the impact of alternative splicing. We previously showed that low recovery of mRNAs from single cells led to erroneous conclusions ab...

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Detalles Bibliográficos
Autores principales: Buen Abad Najar, Carlos F., Burra, Prakruthi, Yosef, Nir, Lareau, Liana F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341514/
https://www.ncbi.nlm.nih.gov/pubmed/35858747
http://dx.doi.org/10.1101/gr.276109.121

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