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Identifying cell state–associated alternative splicing events and their coregulation
Alternative splicing shapes the transcriptome and contributes to each cell's unique identity, but single-cell RNA sequencing (scRNA-seq) has struggled to capture the impact of alternative splicing. We previously showed that low recovery of mRNAs from single cells led to erroneous conclusions ab...
Autores principales: | Buen Abad Najar, Carlos F., Burra, Prakruthi, Yosef, Nir, Lareau, Liana F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9341514/ https://www.ncbi.nlm.nih.gov/pubmed/35858747 http://dx.doi.org/10.1101/gr.276109.121 |
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