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PPARα: A potential therapeutic target of cholestasis

The accumulation of bile acids in the liver leads to the development of cholestasis and hepatocyte injury. Nuclear receptors control the synthesis and transport of bile acids in the liver. Among them, the farnesoid X receptor (FXR) is the most common receptor studied in treating cholestasis. The act...

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Detalles Bibliográficos
Autores principales: Ye, Xiaoyin, Zhang, Tong, Han, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342652/
https://www.ncbi.nlm.nih.gov/pubmed/35924060
http://dx.doi.org/10.3389/fphar.2022.916866

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