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An in vivo Biomarker to Characterize Ototoxic Compounds and Novel Protective Therapeutics

There are no approved therapeutics for the prevention of hearing loss and vestibular dysfunction from drugs like aminoglycoside antibiotics. While the mechanisms underlying aminoglycoside ototoxicity remain unresolved, there is considerable evidence that aminoglycosides enter inner ear mechanosensor...

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Detalles Bibliográficos
Autores principales:	Bellairs, Joseph A., Redila, Van A., Wu, Patricia, Tong, Ling, Webster, Alyssa, Simon, Julian A., Rubel, Edwin W., Raible, David W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342690/ https://www.ncbi.nlm.nih.gov/pubmed/35923755 http://dx.doi.org/10.3389/fnmol.2022.944846

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