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TBK1 is part of a galectin 8 dependent membrane damage recognition complex and drives autophagy upon Adenovirus endosomal escape

Intracellular pathogens cause membrane distortion and damage as they enter host cells. Cells perceive these membrane alterations as danger signals and respond by activating autophagy. This response has primarily been studied during bacterial invasion, and only rarely in viral infections. Here, we in...

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Detalles Bibliográficos
Autores principales: Pied, Noémie, Daussy, Coralie F., Denis, Zoé, Ragues, Jessica, Faure, Muriel, Iggo, Richard, Tschan, Mario P., Roger, Benoit, Rayne, Fabienne, Wodrich, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342788/
https://www.ncbi.nlm.nih.gov/pubmed/35857795
http://dx.doi.org/10.1371/journal.ppat.1010736