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Integrative Conformational Ensembles of Sic1 Using Different Initial Pools and Optimization Methods
Intrinsically disordered proteins play key roles in regulatory protein interactions, but their detailed structural characterization remains challenging. Here we calculate and compare conformational ensembles for the disordered protein Sic1 from yeast, starting from initial ensembles that were genera...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9342850/ https://www.ncbi.nlm.nih.gov/pubmed/35923464 http://dx.doi.org/10.3389/fmolb.2022.910956 |