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IFN-γ and LPS Induce Synergistic Expression of CCL2 in Monocytic Cells via H3K27 Acetylation

BACKGROUND: Overexpression of CCL2 (MCP-1) has been implicated in pathogenesis of metabolic conditions, such as obesity and T2D. However, the mechanisms leading to increased CCL2 expression in obesity are not fully understood. Since both IFN-γ and LPS levels are found to be elevated in obesity and s...

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Detalles Bibliográficos
Autores principales:	Akhter, Nadeem, Kochumon, Shihab, Hasan, Amal, Wilson, Ajit, Nizam, Rasheeba, Al Madhoun, Ashraf, Al-Rashed, Fatema, Arefanian, Hossein, Alzaid, Fawaz, Sindhu, Sardar, Al-Mulla, Fahd, Ahmad, Rasheed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343018/ https://www.ncbi.nlm.nih.gov/pubmed/35923906 http://dx.doi.org/10.2147/JIR.S368352

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