Treatment of COVID-19 by monoclonal antibodies and the traditional Chinese medicine

The mortality rate of the recent global pandemic corona virus disease 2019 (COVID-19) is currently as high as 7%. The SARS-CoV-2 virus is the culprit behind COVID-19. SARS-CoV-2 is an enveloped single-stranded RNA virus, the genome encodes four types of the structural proteins: S protein, E protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Ling, Yuyan, Dong, Yuxuan, Li, Qirui, Huang, Doudou, Li, Zhihui, Chen, Meijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2022
Materias:
Full Length Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343068/
https://www.ncbi.nlm.nih.gov/pubmed/35937968
http://dx.doi.org/10.1016/j.medntd.2022.100159
_version_ 1784760943554592768
author Ling, Yuyan
Dong, Yuxuan
Li, Qirui
Huang, Doudou
Li, Zhihui
Chen, Meijuan
author_facet Ling, Yuyan
Dong, Yuxuan
Li, Qirui
Huang, Doudou
Li, Zhihui
Chen, Meijuan
author_sort Ling, Yuyan
collection PubMed
description The mortality rate of the recent global pandemic corona virus disease 2019 (COVID-19) is currently as high as 7%. The SARS-CoV-2 virus is the culprit behind COVID-19. SARS-CoV-2 is an enveloped single-stranded RNA virus, the genome encodes four types of the structural proteins: S protein, E protein (envelope protein), M protein (matrix protein) and N protein (nucleocapsid protein). In COVID-19, monoclonal antibodies have played a significant role in diagnosis and treatment. This article briefly introduced the development of monoclonal antibodies targeting on S protein and N protein, which represents the main direction of monoclonal antibody drugs used in the diagnosis and treatment of COVID-19. Meanwhile, the traditional Chinese medicine also plays important role in the fight against COVID-19 by regulating human immunity. The article introduced the use of traditional Chinese medicine in fighting against COVID-19.
format Online
Article
Text
id pubmed-9343068
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Author(s). Published by Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-93430682022-08-02 Treatment of COVID-19 by monoclonal antibodies and the traditional Chinese medicine Ling, Yuyan Dong, Yuxuan Li, Qirui Huang, Doudou Li, Zhihui Chen, Meijuan Med Nov Technol Devices Full Length Article The mortality rate of the recent global pandemic corona virus disease 2019 (COVID-19) is currently as high as 7%. The SARS-CoV-2 virus is the culprit behind COVID-19. SARS-CoV-2 is an enveloped single-stranded RNA virus, the genome encodes four types of the structural proteins: S protein, E protein (envelope protein), M protein (matrix protein) and N protein (nucleocapsid protein). In COVID-19, monoclonal antibodies have played a significant role in diagnosis and treatment. This article briefly introduced the development of monoclonal antibodies targeting on S protein and N protein, which represents the main direction of monoclonal antibody drugs used in the diagnosis and treatment of COVID-19. Meanwhile, the traditional Chinese medicine also plays important role in the fight against COVID-19 by regulating human immunity. The article introduced the use of traditional Chinese medicine in fighting against COVID-19. The Author(s). Published by Elsevier B.V. 2022-09 2022-08-01 /pmc/articles/PMC9343068/ /pubmed/35937968 http://dx.doi.org/10.1016/j.medntd.2022.100159 Text en © 2022 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Full Length Article
Ling, Yuyan
Dong, Yuxuan
Li, Qirui
Huang, Doudou
Li, Zhihui
Chen, Meijuan
Treatment of COVID-19 by monoclonal antibodies and the traditional Chinese medicine
title Treatment of COVID-19 by monoclonal antibodies and the traditional Chinese medicine
title_full Treatment of COVID-19 by monoclonal antibodies and the traditional Chinese medicine
title_fullStr Treatment of COVID-19 by monoclonal antibodies and the traditional Chinese medicine
title_full_unstemmed Treatment of COVID-19 by monoclonal antibodies and the traditional Chinese medicine
title_short Treatment of COVID-19 by monoclonal antibodies and the traditional Chinese medicine
title_sort treatment of covid-19 by monoclonal antibodies and the traditional chinese medicine
topic Full Length Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343068/
https://www.ncbi.nlm.nih.gov/pubmed/35937968
http://dx.doi.org/10.1016/j.medntd.2022.100159
work_keys_str_mv AT lingyuyan treatmentofcovid19bymonoclonalantibodiesandthetraditionalchinesemedicine
AT dongyuxuan treatmentofcovid19bymonoclonalantibodiesandthetraditionalchinesemedicine
AT liqirui treatmentofcovid19bymonoclonalantibodiesandthetraditionalchinesemedicine
AT huangdoudou treatmentofcovid19bymonoclonalantibodiesandthetraditionalchinesemedicine
AT lizhihui treatmentofcovid19bymonoclonalantibodiesandthetraditionalchinesemedicine
AT chenmeijuan treatmentofcovid19bymonoclonalantibodiesandthetraditionalchinesemedicine

Ejemplares similares